Highly Selective Palladium-Catalyzed Heck Reactions of Aryl Bromides with Cycloalkenes

Autor:	Matthias Beller, Klaus Köhler, Christian G. Hartung
Rok vydání:	1999
Předmět:	Aryl Organic Chemistry Cyclohexene chemistry.chemical_element Conjugated system Highly selective Biochemistry Medicinal chemistry Catalysis chemistry.chemical_compound chemistry Cyclopentene Organic chemistry Physical and Theoretical Chemistry Selectivity Palladium
Zdroj:	Organic Letters. 1:709-711
ISSN:	1523-7052 1523-7060
DOI:	10.1021/ol9901063
Popis:	[reaction: see text] The influence of palladium catalysts and reaction conditions on the selectivity of Heck reactions of aryl bromides with cyclohexene and cyclopentene has been investigated. It is shown that the addition of DMSO as a cosolvent leads to improved selectivities of nonconjugated aryl olefins. On the other hand, high selectivities for conjugated arylcyclopentenes have been obtained with the catalytic system DMA/Na2CO3/Pd2(dba)3 x dba/PCy3.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4216076d55c6febe4f12b9516e8105 https://doi.org/10.1021/ol9901063 Zobrazit plný text záznamu