Quantifying disease-specific symptom improvement after parathyroid and thyroid surgery using patient-reported outcome measures

Autor: Gustavo Romero-Velez, Talia Burneikis, Samuel J. Zolin, Salem I. Noureldine, Judy Jin, Eren Berber, Vikram D. Krishnamurthy, Joyce Shin, Allan Siperstein
Rok vydání: 2022
Předmět:
Zdroj: The American Journal of Surgery. 224:923-927
ISSN: 0002-9610
DOI: 10.1016/j.amjsurg.2022.04.033
Popis: Patient-reported outcome measures for parathyroid and thyroid disease (PROMPT) is a 30-question, previously validated, survey assessing symptoms on a scale from 0 to 100. Using PROMPT, we aimed to assess symptom improvement for patients undergoing thyroidectomy and parathyroidectomy.Single-center prospective study in which PROMPT was used to assess symptom improvement in patients undergoing parathyroidectomy or thyroidectomy. A postoperative assessment was performed approximately 6 months after surgery and compared to its baseline preoperative assessment.A total of 144 patients completed both assessments (71 parathyroidectomy, 73 thyroidectomy). Parathyroidectomy patients demonstrated significant improvements in all hyperparathyroidism domains (38.2-28.3, p 0.001) regardless of preoperative calcium and parathyroid hormone levels. Thyroidectomy patients experienced improvement in their compressive symptoms (25.6-16.5, p 0.001).PROMPT objectively demonstrates the clinical effectiveness of parathyroidectomy and thyroidectomy in alleviating subjective patient symptoms. PROMPT offers promising use as a standardized metric to assess quality of life improvement within endocrine surgery.
Databáze: OpenAIRE
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