Transabdominal Amniocentesis Is a Feasible and Safe Procedure in Preterm Prelabor Rupture of Membranes
| Autor: | Ivana Musilova, Marian Kacerovsky, Martin Stepan, Tomas Bestvina, Bo Jacobsson, Jaroslav Stranik |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Fetal Membranes Premature Rupture Embryology medicine.medical_specialty Amniotic fluid Umbilical cord Tertiary Care Centers 03 medical and health sciences 0302 clinical medicine Obstetrics and gynaecology Pregnancy Humans Medicine Rupture of membranes Radiology Nuclear Medicine and imaging 030212 general & internal medicine Retrospective Studies Gynecology 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Obstetrics Obstetrics and Gynecology Gestational age Retrospective cohort study General Medicine medicine.anatomical_structure Pediatrics Perinatology and Child Health Amniocentesis Feasibility Studies Gestation Female business |
| Zdroj: | Fetal Diagnosis and Therapy. 42:257-261 |
| ISSN: | 1421-9964 1015-3837 |
| Popis: | Objectives: To determine the feasibility and the complication rate of amniocentesis in a large cohort of women with preterm prelabor rupture of membranes (PPROM). Methods: A retrospective cohort study was conducted in all women with singleton gestation complicated by PPROM at between 24+0 and 36+6 weeks admitted to the Department of Obstetrics and Gynecology, University Hospital Hradec Kralove, Czech Republic between May 2008 and July 2016. Amniocentesis was offered as a part of a routine protocol of PPROM for the detection of microbial invasion of the amniotic cavity and intra-amniotic inflammation. Procedure was performed under ultrasound guidance. A successful procedure was defined as obtaining at least 0.5 mL of amniotic fluid. No more than 2 attempts were performed. Results: In total, 590 women with PPROM were included. Amniocentesis was successful in 96% (567/590). Two amniocentesis attempts were necessary in 9% (55/590) and the transplacental approach was used in 13% (76/590). No association between gestational age at sampling and the amniocentesis failure rate was found (Spearman rho -0.12; p = 0.71). The complication rate was 0.7% (4/590). Two umbilical cord punctures and 2 chorionic plate fetal vessel injuries occurred, without fetal morbidity. Conclusion: Based on our study population, so far the largest published, amniocentesis is a feasible and safe procedure carrying a very low risk of failure or complications in PPROM. |
| Databáze: | OpenAIRE |
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