Protecting Sleep, Promoting Health in Later Life: A Randomized Clinical Trial

Autor: Susan Patrick, Bethany Bell, Linda Serody, Patricia R. Houck, Martica H. Hall, Robert D. Nebes, Michele L. Okun, Jennifer L. Maurer, Salem Bensasi, Sati Mazumdar, Charles F. Reynolds, Mark D. Miller, Eric A. Nofzinger, Mary Amanda Dew
Rok vydání: 2010
Předmět:
Zdroj: Psychosomatic Medicine. 72:178-186
ISSN: 0033-3174
DOI: 10.1097/psy.0b013e3181c870a5
Popis: OBJECTIVES To determine in healthy people aged > or = 75 years 1) if restricting time in bed and education in health sleep practices are superior to an attention-only control condition (i.e., education in healthy dietary practices) for maintaining or enhancing sleep continuity and depth over 2.5 years; and 2) if maintenance or enhancement of sleep continuity and depth promotes the maintenance or enhancement of health-related quality of life. METHODS Single-blind, randomized, clinical trial in a university-based sleep center, enrolling 64 adults (n = 30 women, 34 men; mean age = 79 years) without sleep/wake complaints (e.g., insomnia or daytime sleepiness), followed by randomized assignment to either: 1) restriction of time in bed by delaying bedtime 30 minutes nightly for 18 months, together with education in healthy sleep practices (SLEEP); or 2) attention-only control condition with education in health dietary practices (NUTRITION). RESULTS SLEEP did not enhance sleep continuity or depth; however, compared with NUTRITION, SLEEP was associated with decreased time spent asleep (about 30 minutes nightly over 18 months). Contrary to hypothesis, participants in SLEEP reported a decrement in physical health-related quality of life and an increase in medical burden (cardiovascular illness), relative to NUTRITION. Neither markers of inflammation, body mass index, or exercise explained treatment-related changes in medical burden. CONCLUSIONS Although we cannot exclude a positive effect of education in healthy nutrition, for healthy elderly >75 years of age without sleep complaints, reducing sleep time may be detrimental, whereas allowing more time to sleep (about 7.5 hours nightly) is associated with better maintenance of physical health-related quality of life and stability of medical illness burden over 30 months.
Databáze: OpenAIRE