Cochlear changes in serous labyrinthitis associated with silent otitis media: A human temporal bone study
| Autor: | Sebahattin Cureoglu, Vladimir Tsuprun, Patricia A. Schachern, Serdar Kaya, Michael M. Paparella, Omer Hizli |
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| Přispěvatelé: | Giresun Üniversitesi |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty animal structures Adolescent endocrine system diseases Article 03 medical and health sciences Basal (phylogenetics) Young Adult 0302 clinical medicine Temporal bone Fibrocyte Hair Cells Auditory medicine Cadaver otorhinolaryngologic diseases Humans Endolymphatic hydrops 030223 otorhinolaryngology Child Labyrinthitis Cochlea Spiral ganglion Aged Aged 80 and over business.industry Infant Stria Vascularis Temporal Bone Anatomy Middle Aged medicine.disease Otitis Media Otitis medicine.anatomical_structure Otorhinolaryngology Child Preschool Spiral ligament embryonic structures Female sense organs medicine.symptom business Spiral Ganglion 030217 neurology & neurosurgery |
| Popis: | Hizli, Omer/0000-0001-6822-2679 WOS: 000372213200005 PubMed: 26954857 Purpose: To determine histopathological findings in the cochlea of human temporal bones with serous labyrinthitis. Materials and methods: We compared human temporal bones with serous labyrinthitis (20 cases) associated with silent otitis media and without serous labyrinthitis (20 cases) to study location of serous labyrinthitis, the degree of endolymphatic hydrops, number of spiral ganglion cells and hair cells, loss of fibrocytes in the spiral ligament, and areas of the spiral ligament and stria vascularis. Results: The serous labyrinthitis caused significant loss of outer hair cells in the lower basal (P = 0.006), upper basal (P = 0.005), and lower middle (P = 0.011) cochlear turns, and significant increase in the degree of endolymphatic hydrops than the control group (P = 0.036). No significant difference was found in the loss of inner hair cells, in the number of spiral ganglion cells and fibrocytes in the spiral ligament, and in areas of the stria vascularis and spiral ligament (P > 0.05). Conclusions: Serous labyrinthitis resulted in significant loss of outer hair cells and significant increase in the degree of endolymphatic hydrops. (C) 2016 Elsevier Inc. All rights reserved. National Institute on Deafness and Other Communication Disorders (NIDCD)United States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Institute on Deafness & Other Communication Disorders (NIDCD) [U24 DC011968-01]; International Hearing Foundation; Starkey Hearing Foundation; 5M Lions International; Scientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) This project was funded by the National Institute on Deafness and Other Communication Disorders (NIDCD), grant number U24 DC011968-01; the International Hearing Foundation; the Starkey Hearing Foundation; the 5M Lions International; and the Scientific and Technological Research Council of Turkey (TUBITAK). |
| Databáze: | OpenAIRE |
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