Hidradenitis Suppurativa is Associated with Non-alcoholic Fatty Liver Disease: A Cross-sectional Study
| Autor: | Gregor B.E. Jemec, Luca Schneller-Pavalescu, Isabel Betlloch, Iris González-Villanueva, Pedro Álvarez, Mariana Planells, Inés Poveda, José C. Pascual, Cristina DeGracia, José Ramos |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Hepatic ultrasound Cross-sectional study Liver steatosis Hidradenitis sup-purativa Dermatology Overweight Gastroenterology Body Mass Index liver steatosis Liver disease Non-alcoholic Fatty Liver Disease Internal medicine Prevalence medicine Humans Hidradenitis suppurativa Obesity Risk factor business.industry Fatty liver hepatic ultrasound nutritional and metabolic diseases Acne inversa General Medicine Odds ratio medicine.disease Hidradenitis Suppurativa Cross-Sectional Studies RL1-803 acne inversa medicine.symptom business Body mass index Non-alcoholic fatty liver disease |
| Zdroj: | Acta Dermato-Venereologica, Vol 100, Iss 15, p adv00239 (2020) González-Villanueva, I, DE GRACIA, C, Planells, M, Poveda, I, Álvarez, P, Schneller-Pavelescu, L, Betlloch, I, Jemec, G B, Ramos, J M & Pascual, J C 2020, ' Hidradenitis suppurativa is associated with non-alcoholic fatty liver disease : A cross-sectional study ', Acta Dermato-Venereologica, vol. 100, no. 15, adv00239, pp. 1-5 . https://doi.org/10.2340/00015555-3597 |
| ISSN: | 1651-2057 |
| DOI: | 10.2340/00015555-3597 |
| Popis: | Non-alcoholic fatty liver disease (NAFLD) is currently the most common cause of end-stage liver disease. The aim of this controlled cross-sectional study was to as-sess the association between NAFLD and hidradenitis suppurativa. NAFLD was assessed using hepatic ultra-sound. A total of 125 patients with hidradenitis suppu-rativa and 120 patients without hidradenitis suppu-rativa were recruited, matched for age, sex and body mass index (< 25 or ≥ 25 kg/m2), a risk factor related to NAFLD. Both groups presented similar proportions of overweight or obesity (89.6% vs 90%). Patients with hidradenitis suppurativa presented significantly higher prevalence of NAFLD compared with those with non-hidradenitis suppurativa (57.6% vs 31.7%, p < 0.001). Multivariable analysis confirmed independent association between hidradenitis suppurativa and NAFLD (odds ratio 2.79, 95% confidence interval 1.48–5.25; p = 0.001) besides age, body mass index, hypertension and hypertransaminasaemia. Hidrade-nitis suppurativa is significantly associated with the development of NALFD regardless of the presence of classic metabolic risk factors. |
| Databáze: | OpenAIRE |
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