Preoperative embolization of intracranial meningiomas with Embosphere microspheres
| Autor: | A. Stölzle, S. O. Rodiek, Ch. B. Lumenta |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Adult
Male medicine.medical_specialty Embosphere Microspheres medicine.medical_treatment Preoperative care Neurosurgical Procedures Microsphere Meningioma Preoperative embolization Preoperative Care medicine Meningeal Neoplasms Fluoroscopy Humans Meningeal Neoplasm Embolization Aged Retrospective Studies Aged 80 and over medicine.diagnostic_test business.industry General Medicine Middle Aged medicine.disease Embolization Therapeutic Microspheres Treatment Outcome Surgery Female Neurology (clinical) Radiology business |
| Zdroj: | Minimally invasive neurosurgery : MIN. 47(5) |
| ISSN: | 0946-7211 |
| Popis: | Background To reduce intraoperative bleeding and to facilitate surgery by inducing tumor softening, a preoperative embolization of meningiomas is commonly recommended. Patients and methods We report on our experience with non-resorbable microspheres (Embosphere) in the preoperative endovascular embolization of 17 intracranial meningiomas. After adding contrast media to the particles sized 40-500 micron, the embolization process was followed under fluoroscopy. There was a good passage of microcatheters if high concentrations of particles were avoided. Results The obstruction of the tumor feeders by particles was accompanied by a regression of tumor blush in DSA. CT controls showed a diminished contrast accumulation of the tumors already 1-2 days after embolization. Histologically, Embosphere microspheres were easy detectable with all commonly used staining methods. Embolization triggered, microscopically detectable necrosis was found in 77 % of the tumors. The mean interval between embolization and tumor extirpation was 2.5 days. The average time required for tumor extirpation was 244 minutes, while the average blood loss was 749 ml. Conclusions Our experiences show that Embosphere microspheres are effective embolic agents in obstructing meningeal feeders of preoperatively treated meningiomas. |
| Databáze: | OpenAIRE |
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