Clinicopathologic Profile of Significant Cervical Lymphadenopathy in Children Aged 1–12 Years

Autor: Mohan H. Kulkarni, Rekha B Puranik, Vamseedhar Annam
Rok vydání: 2009
Předmět:
Zdroj: Acta Cytologica. 53:174-178
ISSN: 1938-2650
0001-5547
DOI: 10.1159/000325120
Popis: Objective To emphasize the role of fine needle aspiration cytology '" (FNAC) in etiologic workup in significant cervical lymphadenopathy in children. Study Design A total of336 consecutive children, aged 1 month to 12 years, with significant cervical lymphadenopathy were subjected to FNAC. Children on empirical/specific therapy for lymphadenopathy for > 2 months and children with lymphadenopathy other than cervical region were excluded from this study. Results Of 324 cases, the cytomorphologic features observed were reactive lymphadenitis in 58.02% of cases, granulomatous lymphadenitis in 30.55%, suppurative lymphadenitis in 7.10% and malignancies in 5.62%. The remaining 3.57% of cases were excluded because of inadequate aspiration. The most common cause diagnosed was tuberculosis in 29.01% of cases followed by chronic tonsillopharyngitis in 28.39%, suppurative lymphadenitis in 7.10%, human immune deficiency infection in 5.55% and malignancies in 4.32%. Conclusion FNAC is an important diagnostic modality for the etiologic workup in significant cervical lymphadenopathy in children. It is almost as sensitive and specific as excision lymph node biopsy when an adequate aspirate is examined by expert eyes.
Databáze: OpenAIRE