Autor: |
M. Perez Busquier, E. Calero, M. Rodriguez, P. Castellon Arce, A. Bermudez, L. F. Linares, J. Mesa, C. Ffernandez Crisostomos, C. Garcia, A. Garcia Lopez, A. Valenzuela, A. Povedano, S. Garcia Perez, M. A. Lopez, R. Caliz, F. Garcia Villalba, M. Cano, F. Gines. Martinez, J. Gonzalez, M. A. Caracuel, R. Roldan, M. Guzman Ubeda, A. Gonzalez, I. L. Marenco de la Fuente, E. Rejon, F. Navarro Sarabia, J. Prieto, J. M. Rodriguez, M. Riesco Diaz, F. Manzano, J. Perezbenegas, M. Alepuz Pou |
Rok vydání: |
1997 |
Předmět: |
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Zdroj: |
Clinical rheumatology. 16(2) |
ISSN: |
0770-3198 |
Popis: |
A multicentre, double-blind, randomised, parallel group study was undertaken to investigate the efficacy and safety of aceclofenac (123 patients, 100 mg twice daily) in comparison to piroxicam (117 patients, 20 mg once daily and placebo once daily) in patients with osteoarthritis of the knee. The treatment period of two months was preceded by a washout period of one week duration. On completion of the study, patients in both aceclofenac and piroxicam-treated groups exhibited significant improvement in pain intensity and functional capacity of the affected knee, as represented by the Osteoarthritis Severity Index (OSI) (p |
Databáze: |
OpenAIRE |
Externí odkaz: |
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