Role of Acupoint Area Collagen Fibers in Anti-Inflammation of Acupuncture Lifting and Thrusting Manipulation

Autor: Le Kuai, Jian-Min Xu, Hong-Sheng Dong, Gui-Rong Dong, Huai-Jin Cheng, Guang-Wei Cui, Fan Wang, Tingting Zhang
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Evidence-Based Complementary and Alternative Medicine, Vol 2017 (2017)
Evidence-based Complementary and Alternative Medicine : eCAM
ISSN: 1741-427X
DOI: 10.1155/2017/2813437
Popis: The role of the acupoint area collagen fibers in the efficacy of acupuncture lifting and thrusting (L&T) manipulation will be explored in this paper. 30 male NZW rabbits were randomly divided into 6 groups: sham operation group (Group N), model group (Group M), acupuncture without manipulation group (Group W), acupuncture L&T manipulation group (Group A), collagenase pretreatment group (Group JM), and collagenase pretreatment + acupuncture L&T manipulation group (Group JA). The bacterial endotoxin was used to generate the rabbit fever models. Acupuncture was applied at IL-11. The levels of IL-1β, TNF-α, and IL-4 and the rectal temperature were measured at 2 h, 4 h, and 6 h after modeling and the collagen fiber morphology at acupoint area was observed after 6 hours.Results.As compared with Group N, the levels of IL-1βand TNF-αin Group M were significantly higher; the level of IL-4 was significantly lower (P<0.05). As compared with Group M, IL-1βand TNF-αin Groups W and A were significantly lower and IL-4 was significantly higher (P<0.05). As compared with Group W, IL-1βand TNF-αin Group A were lower and IL-4 was higher (P<0.05). The collagen fiber in Group A was slightly rough, distorted, and fractured. As shown in studies, the endotoxin-induced inflammatory response can be significantly inhibited by acupuncture whose efficacy can also be significantly improved by the manipulations. Collagenase pretreatment may be the first receptor to the mechanical force of the L&T manipulation.
Databáze: OpenAIRE
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