Polymorphisms of human albumin gene after DNA restriction by Hae III endonuclease
| Autor: | Gérard Lucotte, José M. Sala-Trepat, M. Frain, Etienne Mornet, de Souza Sl |
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| Rok vydání: | 1984 |
| Předmět: |
Male
Restriction fragment chemistry.chemical_compound Albumins Complementary DNA Genetics Humans Deoxyribonucleases Type II Site-Specific Gene Genetics (clinical) Polymorphism Genetic biology Albumin Chromosome Mapping Nucleic Acid Hybridization DNA DNA Restriction Enzymes Molecular biology Human genetics Pedigree Restriction enzyme Genes chemistry HaeIII endonuclease biology.protein Female |
| Zdroj: | Human Genetics. 67:48-51 |
| ISSN: | 1432-1203 0340-6717 |
| DOI: | 10.1007/bf00270557 |
| Popis: | Hybridization of albumin clones cDNA with human DNAs digested by several restriction endonucleases reveals two HaeIII polymorphisms. The first polymorphism, H1, is of low frequency (f1 = 0.05); the second, which is validated by family analysis, occurs frequently (f2 = 0.21) and is an intronic polymorphism, probably of substitution--base type. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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