Pallidotomy and quality of life in patients with Parkinson's disease: an early study
| Autor: | Jordi Rumià, Francesc Valldeoriola, Eduard Tolosa, Pablo Martinez-Martin, F. A. Nobbe, José Luis Molinuevo |
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| Rok vydání: | 2000 |
| Předmět: |
Male
medicine.medical_specialty Parkinson's disease medicine.medical_treatment Neurological disorder Globus Pallidus Central nervous system disease Stereotaxic Techniques Quality of life Rating scale medicine Humans Pallidotomy Dominance Cerebral Aged Neurologic Examination Parkinson Disease Middle Aged medicine.disease humanities Mood Neurology Motor Skills Physical therapy Quality of Life Female Neurology (clinical) Abnormal Involuntary Movement Scale Psychology Follow-Up Studies |
| Zdroj: | Movement disorders : official journal of the Movement Disorder Society. 15(1) |
| ISSN: | 0885-3185 |
| Popis: | The purpose of this study was to analyze the effect of stereotactic neurophysiologically guided pallidotomy on health-related quality of life (QoL) of patients with Parkinson's disease (PD). Eleven patients with PD (seven men, four women; mean age, 57.2 years; mean duration of disease, 14 years) with motor complications refractory to medical therapy underwent unilateral pallidotomy. Clinical assessment was carried out a week before surgery and 4 months after the surgical procedure and was based on the Core Assessment Program for Intracerebral Transplantations protocol. QoL was measured by means of the PDQ-39. A set of rating scales (Hoehn & Yahr, Unified Parkinson's Disease Rating Scale, Schwab and England, Northwestern University Disability Scale of Walking, Abnormal Involuntary Movement Scale), timed tests, and self-evaluations of motor function and mood were applied. Improvement was found in dyskinesias (74%) and off-period disability (42%). Cardinal motor signs improved significantly (30%–59%). Four dimensions of the PDQ-39 (Mobility, ADL, Emotions, Bodily Pain) showed a significant improvement (p |
| Databáze: | OpenAIRE |
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