Diplomyelia: Caudal duplication of the neural tube in mice
| Autor: | S. B. Cogliatti |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Tail
Heterozygote Embryology Brachyury Health Toxicology and Mutagenesis Notochord Gestational Age Biology Toxicology medicine.disease_cause Mice Gene duplication medicine Animals Neural Tube Defects Mutation Fetus Homozygote Neural tube Embryo Anatomy Spinal cord Mice Mutant Strains Phenotype medicine.anatomical_structure embryonic structures Developmental Biology |
| Zdroj: | Teratology. 34:343-352 |
| ISSN: | 1096-9926 0040-3709 |
| Popis: | Diplomyelia (duplication of the neural tube or spinal cord) was studied histologically in nine cases of T/+ mouse embryos at 10-15 days of gestation. Grüneberg investigated T/+ fetuses and interpreted the extra neural tube to be notochord, but a reexamination of this material demonstrated that the interpretation is incorrect. Diplomyelia is produced in the mutations Fused, Kinky, vestigial tail, homozygous Brachyury, and t-haplotype t9 and in the new mutation, NM 529, described here. |
| Databáze: | OpenAIRE |
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