THE INFLUENCE OF THE PINEAL GLAND ON NITROGEN METABOLISM

Autor: Violeta Ionescu, Rodica Marcean, Lydia Nanu-Ionescu, Ioana Milcu
Rok vydání: 1969
Předmět:
Zdroj: Journal of Endocrinology. 45:175-181
ISSN: 1479-6805
0022-0795
DOI: 10.1677/joe.0.0450175
Popis: SUMMARY The influence of the pineal gland on protein metabolism was investigated by using a test previously devised for studying the anabolic action of growth hormone. This test consists in measuring the accumulation of urea in blood after the intravenous administration of an amino acid mixture to nephrectomized rats injected with the test substance. Like growth hormone, pineal extract significantly reduced the quantity of urea formed, suggesting an anabolic action. In contrast, in pinealectomized animals, the quantity of urea formed significantly increased when compared with controls.
Databáze: OpenAIRE