Prevalence of Potentially Inappropriate Medication use in older drivers

Autor: Guohua Li, Howard F. Andrews, Stanford Chihuri, Barbara H. Lang, Cheng Shiun Leu, David P. Merle, Abigail Gordon, Thelma J. Mielenz, David Strogatz, David W. Eby, Marian E. Betz, Carolyn DiGuiseppi, Vanya C. Jones, Lisa J. Molnar, Linda L. Hill, The LongROAD Research Team
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Gerontology
Male
Beers criteria
medicine.medical_specialty
Automobile Driving
Aging
medicine.medical_treatment
Psychological intervention
Beers Criteria
Inappropriate Prescribing
lcsh:Geriatrics
Occupational safety and health
Cohort Studies
03 medical and health sciences
0302 clinical medicine
hemic and lymphatic diseases
Prevalence
Medicine
Humans
030212 general & internal medicine
Longitudinal Studies
Prospective Studies
Potentially Inappropriate Medication List
Aged
Geriatrics
Aged
80 and over
Medication use
Rehabilitation
business.industry
Odds ratio
Confidence interval
lcsh:RC952-954.6
Cross-Sectional Studies
Driving safety
Older adults
Female
Independent Living
Geriatrics and Gerontology
business
human activities
Potentially inappropriate medications
030217 neurology & neurosurgery
Research Article
Zdroj: BMC Geriatrics, Vol 19, Iss 1, Pp 1-8 (2019)
BMC Geriatrics
ISSN: 1471-2318
Popis: Background Potentially Inappropriate Medication (PIM) use has been studied in a variety of older adult populations across the world. We sought to examine the prevalence and correlates of PIM use in older drivers. Methods We applied the American Geriatrics Society 2015 Beers Criteria to baseline data collected from the “brown-bag” review of medications for participants of the Longitudinal Research on Aging Drivers (LongROAD) study to examine the prevalence and correlates of PIM use in a geographically diverse, community-dwelling sample of older drivers (n = 2949). Proportions of participants who used one or more PIMs according to the American Geriatrics Society 2015 Beers Criteria, and estimated odds ratios (ORs) and 95% confidence intervals (CIs) of PIM use associated with participant characteristics were calculated. Results Overall, 18.5% of the older drivers studied used one or more PIM. The most commonly used therapeutic category of PIM was benzodiazepines (accounting for 16.6% of the total PIMs identified), followed by nonbenzodiazepine hypnotics (15.2%), antidepressants (15.2%), and first-generation antihistamines (10.5%). Compared to older drivers on four or fewer medications, the adjusted ORs of PIM use were 2.43 (95% CI 1.68–3.51) for those on 5–7 medications, 4.19 (95% CI 2.95–5.93) for those on 8–11 medications, and 8.01 (95% CI 5.71–11.23) for those on ≥12 medications. Older drivers who were female, white, or living in urban areas were at significantly heightened risk of PIM use. Conclusion About one in five older drivers uses PIMs. Commonly used PIMs are medications known to impair driving ability and increase crash risk. Implementation of evidence-based interventions to reduce PIM use in older drivers may confer both health and safety benefits. Trial registration Not applicable.
Databáze: OpenAIRE
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