Correction of anaemia and thrombocytopenia in a case of adult Type I osteopetrosis with recombinant human erythropoietin (rHuEPO)
| Autor: | Niki Stavrogianni, Christos Poziopoulos, Christos Meletis, Evi Michali, Stathis Vavourakis, John Meletis, Kostas Konstantopoulos, George Vaiopoulos, Michalis Samarkos, Xenophon Yataganas, Dimitris Loukopoulos |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Anemia medicine.medical_treatment hemic and lymphatic diseases medicine Humans Young adult Bone Marrow Diseases Erythropoietin Chemotherapy business.industry Osteopetrosis Hematology medicine.disease Thrombocytopenia Recombinant Proteins Haematopoiesis Nandrolone Immunology Female Complication business medicine.drug |
| Zdroj: | British Journal of Haematology. 89:911-913 |
| ISSN: | 0007-1048 |
| Popis: | A case of adult osteopetrosis Type I was diagnosed in a 22-year-old female. She presented for investigation of anaemia with 'myelophthisic' characteristics and extramedullary haemopoiesis which was resistant to haematinics, nandrolone and low-dose corticosteroids. She became progressively transfusion-dependent with gradually worsening thrombocytopenia. She was successfully treated with recombinant erythropoietin. Anaemia as well as thrombocytopenia were corrected. There appeared to be a synergistic action of erythropoietin with steroids. |
| Databáze: | OpenAIRE |
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