Osseointegration is improved by coating titanium implants with a nanostructured thin film with titanium carbide and titanium oxides clustered around graphitic carbon
| Autor: | Roberto Scandurra, Nicola Di Girolamo, Paolo Selleri, Anna Scotto d'Abusco, Francesca Veronesi, Caterina Alexandra Ioannidu, Viola Garbarino, Gianluca Panzini, Milena Fini, Fabiana Superti, Giovanni Longo, Laura Politi, Gianluca Giavaresi, Carlo Misiano, Alberto Palattella |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Materials science
Xylenol orange Graphitic carbon Bone Screws chemistry.chemical_element Bioengineering 02 engineering and technology engineering.material 010402 general chemistry 01 natural sciences Osseointegration Titanium carbide Biomaterials chemistry.chemical_compound Coating Coated Materials Biocompatible Animals Animal model Femur Thin film Titanium Osteoblasts Metallurgy Ion plating Prostheses and Implants 021001 nanoscience & nanotechnology 0104 chemical sciences Nanostructures Nanostructured thin film chemistry Mechanics of Materials engineering Graphite Implant Rabbits 0210 nano-technology animal model graphitic carbon nanostructured thin film osseointegration osteoblasts titanium carbide materials science (all) condensed matter physics mechanics of materials mechanical engineering Biomedical engineering |
| Zdroj: | Materials science & engineering. C, Biomimetic materials, sensors and systems 70 (2017): 264–271. doi:10.1016/j.msec.2016.08.076 info:cnr-pdr/source/autori:Veronesi F.; Giavaresi G.; Fini M.; Longo G.; Ioannidu C.A.; Scotto d'Abusco A.; Superti F.; Panzini G.; Misiano C.; Palattella A.; Selleri P.; Di Girolamo N.; Garbarino V.; Politi L.; Scandurra R./titolo:Osseointegration is improved by coating titanium implants with a nanostructured thin film with titanium carbide and titanium oxides clustered around graphitic carbon/doi:10.1016%2Fj.msec.2016.08.076/rivista:Materials science & engineering. C, Biomimetic materials, sensors and systems (Print)/anno:2017/pagina_da:264/pagina_a:271/intervallo_pagine:264–271/volume:70 |
| DOI: | 10.1016/j.msec.2016.08.076 |
| Popis: | Titanium implants coated with a 500 nm nanostructured layer, deposited by the Ion Plating Plasma Assisted (IPPA) technology, composed of 60% graphitic carbon, 25% titanium oxides and 15% titanium carbide were implanted into rabbit femurs whilst into the controlateral femurs uncoated titanium implants were inserted as control. At four time points the animals were injected with calcein green, xylenol orange, oxytetracycline and alizarin. After 2, 4 and 8 weeks femurs were removed and processed for histology and static and dynamic histomorphometry for undecalcified bone processing into methylmethacrylate, sectioned, thinned, polished and stained with Toluidine blue and Fast green. The overall bone-implant contacts rate (percentage of bone-implant contacts/weeks) of the TiC coated implant was 1.6 fold than that of the uncoated titanium implant. The histomorphometric analyses confirmed the histological evaluations. More precisely, higher Mineral Apposition Rate (MAR, ?m/day) (p |
| Databáze: | OpenAIRE |
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