Four-year experience with liver transplantation in Saudi Arabia

Autor: G Geldhof, T.J. Bhatti, M Al Sebayel, C.B Ramirez, A.T. Kizilisik, A Abdullah
Rok vydání: 1998
Předmět:
Zdroj: Transplantation proceedings. 30(7)
ISSN: 0041-1345
Popis: The liver transplant program at the King Fahad National Guard Hospital in Riyadh, Saudi Arabia, was launched in January 1994. Up to November 1997, a total of 84 procedures have been performed on 77 patients. Table 1 shows the demographics of transplanted patients. Table 2 shows the indications for transplantation in our population. Hepatitis C virus (HCV) infection continues to be the leading cause of liver disease. We continue to use the standard surgical technique with utilization of venovenous bypass in more than 80% of the cases. The piggyback technique was used in nine cases and biliary anastomosis was performed with either Roux-en-Y or duct-to-duct anastomosis. The T-tube has not been utilized in the last 2.5 years of the program. Immunosuppression was standardized to FK 506, steroids being discontinued 3 months following transplant. Of the 16 patients who died, 2 died after the first year. Table 3 details the causes of death in these patients. Table 4 outlines the technical complications in 84 transplant procedures. We continue to have a low rejection rate of 31%. All the cases responded to steroids without resorting to monoclonal antibody treatment. The leading cause of death was infectious complications. Primary nonfunction occurred in one patient only. However, severe dysfunction with an alanine transaminase level (ALT) of greater than 3000 occurred in 27% of the patients.
Databáze: OpenAIRE
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