Epidemiologic case investigation on the zoonotic transmission of Staphylococcus aureus infection from goat to veterinarians

Autor: Silvia Piva, Mariana Roccaro, Simone Ambretti, Lucia De Castelli, Monica Cricca, Barbara Brunetti, Angelo Peli, Irene Ferrero, Alessandra Scagliarini, Andrea Serraino, Angelo Romano, Federica Giacometti, Elisabetta Mondo, Giuseppe Merialdi, Jole Mariella
Přispěvatelé: Piva S., Mariella J., Cricca M., Giacometti F., Brunetti B., Mondo E., De Castelli L., Romano A., Ferrero I., Ambretti S., Roccaro M., Merialdi G., Scagliarini A., Serraino A., Peli A.
Rok vydání: 2021
Předmět:
0301 basic medicine
Staphylococcus aureus
Bacterial Zoonoses
subtyping
Epidemiology
Short Communication
030106 microbiology
030231 tropical medicine
Short Communications
professional zoonosi
Abortion
medicine.disease_cause
Abomasum
professional zoonosis
Veterinarians
Microbiology
Enterotoxins
03 medical and health sciences
Fatal Outcome
0302 clinical medicine
Pregnancy
Occupational Exposure
medicine
Animals
Metritis
reproductive and urinary physiology
Fetus
Goat Diseases
General Veterinary
General Immunology and Microbiology
business.industry
Transmission (medicine)
Goats
goat
Zoonosis
Public Health
Environmental and Occupational Health
Gene Expression Regulation
Bacterial
Abortion
Veterinary
Staphylococcal Infections
medicine.disease
Dystocia
abortion
Infectious Diseases
Staphylococcus aureu
Herd
Female
business
Zdroj: Zoonoses and Public Health
ISSN: 1863-2378
1863-1959
DOI: 10.1111/zph.12836
Popis: Staphylococcus aureus infection led to a case of goat abortion, and four veterinarians contracted S.aureus infection from the goat during and after the abortion. Three veterinarians assisted a doe during the dystocic delivery of a dead foetus. Seventy-two hours after the dystocia, which ended with the goat's death, the veterinarians who assisted during the kidding and the veterinarian who performed the necropsy showed the presence of multiple, isolated, painful pustules 1–5mm in diameter located along their forearms and knees. S.aureus was isolated from the pustules of the veterinarians, the placenta and uterus of the goat, the organs (brain, thymus gland, abomasum, liver and spleen) of the foetus, the scrotum and eye swabs of the buck, and mammary pustules of another goat from the same herd. Histological analysis revealed purulent metritis and inflammation of the placental cotyledons. Additional investigations eliminated the chances of other infections. S.aureus isolates recovered from the veterinarians, goats, foetus and buck were sensitive to the tested anti-microbials and did not encode staphylococcal enterotoxin genes (sea, ser, sep, see, seg and sei). The isolates were closely related, as indicated by the results of Fourier-transform infrared spectroscopy and comparative whole-genome sequencing analysis. The results of this study clearly support the hypothesis that an episode of professional zoonosis was caused by S.aureus infection during the abortion and also highlight the need for bacterial subtyping in epidemiological surveys.
Databáze: OpenAIRE
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