Mycotoxic porcine nephropathy and spontaneous occurrence of ochratoxin A residues in kidneys of slaughtered swine
| Autor: | Srdjan Stefanovic, R Dragan Milicevic, Aleksandra Dakovic, B Verica Juric, Miljan Jovanovic, I Zoran Petrovic |
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| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Ochratoxin A
pig medicine.medical_specialty Kidney Pathology Necrosis Biology medicine.disease Nephrotoxicity Nephropathy chemistry.chemical_compound medicine.anatomical_structure Vacuolization chemistry medicine General Earth and Planetary Sciences nephropathy Histopathology medicine.symptom lcsh:Science (General) Ochratoxin General Environmental Science lcsh:Q1-390 |
| Zdroj: | Zbornik Matice Srpske za Prirodne Nauke, Vol 2009, Iss 116, Pp 81-90 (2009) |
| ISSN: | 0352-4906 |
| Popis: | In order to find information on the occurrence of mycotoxic porcine nephropathy in Serbia, during a six month period (2006/2007) samples of kidney from individual healthy slaughtered pigs were collected (n=90) and analyzed by HPLC for ochratoxin A. In addition, histological examinations were carried out. The incidence of OTA in kidney was 33,3% and varied between 0.17-52.5 ng/g. Histopathological examination of kidneys confirmed tubulopathies with oedema and cell vacuolization. In addition, hemorrhages and necrosis of proximal kidney tubules cells were found. These findings indicate that it is likely that most of the kidney injury is related to ochratoxin A and other nephrotoxic compounds which enhance the toxicity of OTA. |
| Databáze: | OpenAIRE |
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