Pediatric hospitalizations associated with 2009 pandemic influenza A (H1N1) in Argentina
| Autor: | Valeria S. Santidrian, Gabriela Gregorio, Victoria I. Sanchez Mercol, Fernanda Santucho, Ana Borsa, Diego R. Hijano, Maria I. Lutz, Guillermina A. Melendi, Lidia C. Albano, James D. Chappell, Jimena Bugna, Maria D. Neder, Margarita Ramonet, Fernando P. Polack, Natalia Reynoso, Mercedes Garcia Domínguez, Liliana Alvarez, Patricia Landa, Marco A. Espinoza, Romina Libster, Maria Emilia Gutierrez Meyer, M. Soledad Areso, Rina Moreno, Mariana Dunaiewsky, Ricardo S. Dalamón, Norma Boloñati, Rodrigo M. Egües Almeida, Ana Pota, Alicia L. Panigasi, María C Davenport, Guillermina Mosca, Ariel Karolinski, Liliana Saligari, Elias Alterman, Graciela Cabral, Maria C. Guglielmo, Vilma Savy, Silvina Coviello, Kathryn M. Edwards, Angel Bonina, Fernando Ferrero, Elsa Baumeister, Miriam Bruno, Nora Luedicke, Mauricio T. Caballero, Juan Carlos Peuchot, María L Cavalieri, Tomas Gilligan, María de la Paz Del Valle |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Adolescent Staphylococcus Prevalence Argentina Comorbidity medicine.disease_cause Severity of Illness Index law.invention Disease Outbreaks Age Distribution Influenza A Virus H1N1 Subtype law Pandemic Influenza Human medicine Influenza A virus Pneumonia Bacterial Humans Child Hypoxia business.industry Mortality rate Infant Newborn virus diseases Infant Pediatric Death General Medicine medicine.disease Intensive care unit Infant mortality Hospitalization Pneumonia Streptococcus pneumoniae Child Preschool Female business |
| Zdroj: | The New England journal of medicine. 362(1) |
| ISSN: | 1533-4406 |
| Popis: | BACKGROUND While the Northern Hemisphere experiences the effects of the 2009 pandemic influenza A (H1N1) virus, data from the recent influenza season in the Southern Hemisphere can provide important information on the burden of disease in children. METHODS We conducted a retrospective case series involving children with acute infection of the lower respiratory tract or fever in whom 2009 H1N1 influenza was diagnosed on reverse-transcriptase polymerase-chain-reaction assay and who were admitted to one of six pediatric hospitals serving a catchment area of 1.2 million children. We compared rates of admission and death with those among age-matched children who had been infected with seasonal influenza strains in previous years. RESULTS Between May and July 2009, a total of 251 children were hospitalized with 2009 H1N1 influenza. Rates of hospitalization were double those for seasonal influenza in 2008. Of the children who were hospitalized, 47 (19%) were admitted to an intensive care unit, 42 (17%) required mechanical ventilation, and 13 (5%) died. The overall rate of death was 1.1 per 100,000 children, as compared with 0.1 per 100,000 children for seasonal influenza in 2007. (No pediatric deaths associated with seasonal influenza were reported in 2008.) Most deaths were caused by refractory hypoxemia in infants under 1 year of age (death rate, 7.6 per 100,000). CONCLUSIONS Pandemic 2009 H1N1 influenza was associated with pediatric death rates that were 10 times the rates for seasonal influenza in previous years. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|