Maternal preeclampsia and risk for cardiovascular disease in offspring
| Autor: | Guadalupe Herrera-Garcia, Stephen Contag |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Gestational hypertension
medicine.medical_specialty Offspring Blood Pressure Global Health Preeclampsia Coronary artery disease Pre-Eclampsia Pregnancy Risk Factors Internal medicine Diabetes mellitus Internal Medicine medicine Humans business.industry Incidence Infant Newborn medicine.disease Prognosis Blood pressure Cardiovascular Diseases Hypertensive disease of pregnancy Cardiology Female Metabolic syndrome business |
| Zdroj: | Current hypertension reports. 16(9) |
| ISSN: | 1534-3111 |
| Popis: | Hypertensive disease of pregnancy (HDP) has been associated with elevated lifetime cardiovascular risk, including stroke, myocardial disease, coronary artery disease, and peripheral arterial disease. These two entities share common risk factors such as obesity, insulin resistance, diabetes, and hypertension. This article will evaluate the current literature on the maternal and fetal cardiovascular risks posed by HDP. The landmark study by Barker et al. demonstrated increased cardiovascular risk in growth-restricted infants, which may also be associated with HDP. Research has demonstrated the effects that HDP may have on the vascular and nephron development in offspring, particularly with respect to endothelial and inflammatory markers. In order to control for confounding variables and better understand the relationship between HDP and lifetime cardiovascular risk, future research will require following blood pressure and metabolic profiles of the parturients and their offspring. |
| Databáze: | OpenAIRE |
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