Maturation-inhibiting activity in growing mouse oocytes
| Autor: | Jr J Fulka |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Cytoplasm
Mice Inbred A Maturation-Promoting Factor Maturation promoting factor Cell Fusion Mice Meiosis medicine Animals Growth Substances Genetics Cell Nucleus Cell fusion biology Vesicle Oocyte Cell biology Cell nucleus medicine.anatomical_structure Giant cell biology.protein Oocytes Intercellular Signaling Peptides and Proteins Female Peptides Developmental Biology |
| Zdroj: | Cell differentiation. 17(1) |
| ISSN: | 0045-6039 |
| Popis: | Growing mouse oocytes incompetent to resume meiosis were fused with fully grown immature mouse oocytes and cultured for 20-24 h. In giant cells that developed, two intact germinal vesicles remained well conserved in all cases. We propose that the cytoplasm of growing oocytes possesses a maturation-inhibiting activity which is able to arrest, after fusion, nuclear maturation in fully grown oocytes competent to mature spontaneously. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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