Effects of infant formula composition on long-term metabolic health
| Autor: | I. Le Huërou-Luron, S. Blat, Marion Lemaire |
|---|---|
| Přispěvatelé: | Groupe Lactalis, Nutrition, Métabolismes et Cancer (NuMeCan), Institut National de la Recherche Agronomique (INRA)-Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), M.L. is employed by Lactalis R&D., ProdInra, Archive Ouverte, Institut National de la Recherche Agronomique (INRA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Synbiotics neonatal feeding Medicine (miscellaneous) Physiology microbiote digestif Gut flora Breast milk Protein content 03 medical and health sciences Metabolic Diseases Humans Medicine alimentation neonatale métabolisme Metabolic health 2. Zero hunger Milk Human biology Human studies gut microbiota business.industry Infant Newborn Infant programmation nutritionnelle biology.organism_classification Infant Formula Bottle Feeding Gastrointestinal Microbiome 3. Good health [SDV.AEN] Life Sciences [q-bio]/Food and Nutrition Breast Feeding 030104 developmental biology Infant formula early nutrition nutrition infantile business nutritional programming Breast feeding metabolism [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition |
| Zdroj: | Journal of Developmental Origins of Health and Disease Journal of Developmental Origins of Health and Disease, 2018, 9 (6), pp.573-589. ⟨10.1017/S2040174417000964⟩ Journal of Developmental Origins of Health and Disease, Cambridge University Press, 2018, 9 (6), pp.573-589. ⟨10.1017/S2040174417000964⟩ |
| ISSN: | 2040-1744 2040-1752 |
| DOI: | 10.1017/S2040174417000964⟩ |
| Popis: | International audience; Early nutrition may have long-lasting metabolic impacts in adulthood. Even though breast milk is the gold standard, most infants are at least partly formula-fed. Despite obvious improvements, infant formulas remain perfectible to reduce the gap between breastfed and formula-fed infants. Improvements such as reducing the protein content, modulating the lipid matrix and adding prebiotics, probiotics and synbiotics, are discussed regarding metabolic health. Numerous questions remain to be answered on how impacting the infant formula composition may modulate the host metabolism and exert long-term benefits. Interactions between early nutrition (composition of human milk and infant formula) and the gut microbiota profile, as well as mechanisms connecting gut microbiota to metabolic health, are highlighted. Gut microbiota stands as a key actor in the nutritional programming but additional well-designed longitudinal human studies are needed. |
| Databáze: | OpenAIRE |
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