Stable Tetrodotoxin Production by Bacillus sp. Strain 1839
| Autor: | Timur Yu. Magarlamov, Daria I. Melnikova, Anna E. Vlasenko |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
spores
Pharmaceutical Science Bacillus Bacillus sp TTX Tandem mass spectrometry Microbiology 03 medical and health sciences chemistry.chemical_compound Drug Discovery Pharmacology Toxicology and Pharmaceutics (miscellaneous) tetrodotoxin 030304 developmental biology 0303 health sciences biology Strain (chemistry) HPLC-MS/MS Host (biology) musculoskeletal neural and ocular physiology fungi 030302 biochemistry & molecular biology TTX-producing bacteria biology.organism_classification Isolation (microbiology) Spore chemistry Tetrodotoxin |
| Zdroj: | Marine Drugs Volume 17 Issue 12 |
| ISSN: | 1660-3397 |
| DOI: | 10.3390/md17120704 |
| Popis: | For the first time, tetrodotoxin (TTX) was detected in a bacterial strain after five years of cultivation in laboratory conditions since its isolation from the animal host. A reliable method suitable for bacterial samples, high-performance liquid chromatography with tandem mass spectrometry, was used for toxin detection in spore and vegetative cultures of Bacillus sp. 1839. TTX was detected in a spore culture of the strain. |
| Databáze: | OpenAIRE |
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