Synthesis, characterization, and biological evaluation of silver(I) complexes of N′-(1-(pyrazin-2-yl)ethylidene)picolinohydrazide
| Autor: | Qing-Ling Ren, Lin-Xia Song, Jie Qin, Shan-Shan Zhao, Shao-Song Qian |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
chemistry.chemical_classification
biology 010405 organic chemistry Stereochemistry Serum albumin Hydrazone 010402 general chemistry 01 natural sciences 0104 chemical sciences chemistry Materials Chemistry biology.protein Hydrazone ligand Physical and Theoretical Chemistry Antibacterial activity Biological evaluation |
| Zdroj: | Journal of Coordination Chemistry. 69:227-237 |
| ISSN: | 1029-0389 0095-8972 |
| DOI: | 10.1080/00958972.2015.1110240 |
| Popis: | Three Ag+ complexes, [Ag(L)(NO3)]n (1), {[Ag(L)]·SbF6·CH2Cl2}n (2), and {[Ag(L)]·SO3CF3·CHCl3}n (3), based on a hydrazone ligand L have been obtained (L = N′-(1-(pyrazin-2-yl)ethylidene)picolinohydrazide) and characterized. Complexes 1–3 all show 1-D chain-like structures. Their antibacterial activity and interaction with serum albumin were investigated. These results indicate that these complexes show good antibacterial activities and binding affinity to serum albumin. |
| Databáze: | OpenAIRE |
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