Diffuse axonal injury: detection of changes in anisotropy of water diffusion by diffusion-weighted imaging
| Autor: | D. Fong, Wilfred C. G. Peh, M. K. Yuen, K. M. Leung, J. H. M. Chan, E. Y. K. Tsui, K. K. L. Fung, K. F. Fok |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Diffuse Axonal Injury Diffusion Anisotropy White matter Nuclear magnetic resonance medicine Humans Radiology Nuclear Medicine and imaging Diffusion (business) Axon Anisotropy business.industry Diffuse axonal injury Head injury Brain Water medicine.disease medicine.anatomical_structure Diffusion Magnetic Resonance Imaging Female Neurology (clinical) Cardiology and Cardiovascular Medicine business Diffusion MRI |
| Zdroj: | Europe PubMed Central |
| ISSN: | 0028-3940 |
| Popis: | Myelinated axons of white matter demonstrate prominent directional differences in water diffusion. We performed diffusion-weighted imaging on ten patients with head injury to explore the feasibility of using water diffusion anisotropy for quantitating diffuse axonal injury. We showed significant decrease in diffusion anisotropy indices in areas with or without signal abnormality on T2 and T2*-weighted images. We conclude that the water diffusion anisotropy index a potentially useful, sensitive and quantitative way of diagnosing and assessing patients with diffuse axonal injury. |
| Databáze: | OpenAIRE |
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