The Second- vs First-wave COVID-19: More of the Same or a Lot Worse? A Comparison of Mortality between the Two Waves in Patients Admitted to Intensive Care Units in Nine Hospitals in Western Maharashtra

Autor: Zafer Khan Amanulla, Ameya Joshi, Sourabh Ambapkar, Sushma Gurav, Atul P Kulkarni, Subhal Dixit, Abhijit M Deshmukh, Vinod Gosavi, Saanvi Ambapkar, Kapil Zirpe, Gowri Sayiprasad, Bindu Mulakavalupil, Priya Ranganathan, Vatsal Kothari, Anmol Zirpe, Madhura Bapte, Shrikant Shastrabuddhe, Charlotte Saldhanah, Rahul A Pandit, Sweta Singh, Mukund Manohar Joshi, Sayi Prasad, Khalid I Khatib
Rok vydání: 2021
Předmět:
Zdroj: Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine
ISSN: 1998-359X
0972-5229
Popis: Background India, along with the rest of the world, faced the challenging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. The second wave in India lagged behind that in the Western world, due to different timing of seasons. There is scarce data about the differences between the two waves, for intensive care unit (ICU) patients. We present the data of 3,498 patients from 9 ICUs of western Maharashtra. Materials and methods We collected prospective data of hospitalized, RT-PCR confirmed, coronavirus-2019 (COVID-19) patients, from nine tertiary centers, after institutional ethics committee (IEC) approval. Then, we segregated and analyzed the data of patients admitted to the ICU, for comorbidities, high-resolution computed tomography (HRCT) score, ventilatory support, etc. The primary outcomes were ICU and hospital mortality. We also performed multivariable analysis for predictors of ICU mortality. Results Overall, there were 3,498 ICU patients. In the first wave, 1,921 patients needed ICU admission, while in the second wave, 1,577 patients. Patients in the second wave had significantly higher ICU (26.1 vs 13.4%, p
Databáze: OpenAIRE