CT enteroclysis/enterography findings in drug-induced small-bowel damage
| Autor: | Naofumi Matsunaga, S Hashimoto, K Shimizu, H Onoda, Yasuo Washida, I Sakaida, T Kishi |
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| Rok vydání: | 2014 |
| Předmět: |
Male
Drug Enteroscopy medicine.medical_specialty media_common.quotation_subject Capsule Endoscopy Gastroenterology law.invention Diagnosis Differential Capsule endoscopy law Internal medicine Intestine Small medicine Humans Radiology Nuclear Medicine and imaging Aged Retrospective Studies media_common Aged 80 and over CT enteroclysis Aspirin Full Paper business.industry Anti-Inflammatory Agents Non-Steroidal Retrospective cohort study General Medicine Middle Aged Radiography Intestinal Diseases Videocapsule Endoscopy Female Differential diagnosis business medicine.drug |
| Zdroj: | The British Journal of Radiology. 87:20140367 |
| ISSN: | 1748-880X 0007-1285 |
| DOI: | 10.1259/bjr.20140367 |
| Popis: | To evaluate the CT enteroclysis (CTE)/enterography findings of patients with small-bowel mucosal damage induced by aspirin or non-steroidal anti-inflammatory drugs (NSAIDs) and to compare these findings with the duration of drug use and endoscopic findings.CTE findings of 11 patients (22 lesions) with drug-induced small-bowel damage were reviewed, including 8 NSAID users and 3 aspirin users. Three patients were short-term users (6 months or shorter) and eight were long-term users (3 years or longer). Nine patients also underwent videocapsule endoscopy (VCE) or double-balloon enteroscopy (DBE).Small-bowel abnormalities were visible in 8 of 11 patients (73%) on CTE. Multiple lesions were seen in five patients, including all short-term users. Lesions were classified into three types. Type 1 (mucosal patchy enhancement) was found in four of eight patients (50%, 12 lesions) all were short-term users. Small erosions with mild oedema/redness were shown by DBE. Type 2 (homogeneous hyperenhancement) was found in two of eight patients (25%, four lesions) who were long-term users. Large ulcers with marked oedema/redness were shown by DBE. Type 3 (stratification enhancement) was found in four of eight patients (50%, six lesions), both short-term and long-term users. Annular or large ulcers with strictures were shown by VCE or DBE.On CTE, Type 1 lesions in patients with mostly short-term aspirin or NSAID use, Type 2 lesions in patients with long-term use and Type 3 lesions in both types of patients were detected. CTE may have usefulness for the detection of mild damage.Small-bowel abnormalities owing to aspirin or NSAID present with three different patterns on CTE. |
| Databáze: | OpenAIRE |
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