Magnetic resonance elastography to estimate brain stiffness: Measurement reproducibility and its estimate in pseudotumor cerebri patients
| Autor: | Brian Raterman, Prateek Kalra, Arunark Kolipaka, Xiaokui Mo, Sangmin Cha, Wael M. Marashdeh, Peter A. Wassenaar, Eric C. Bourekas, Bradley Gans |
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| Rok vydání: | 2017 |
| Předmět: |
musculoskeletal diseases
Adult Male animal structures Intracranial Pressure Pseudotumor cerebri Severity of Illness Index Article 030218 nuclear medicine & medical imaging 03 medical and health sciences Young Adult 0302 clinical medicine Cerebrospinal fluid medicine Humans Radiology Nuclear Medicine and imaging Intracranial pressure Reproducibility Pseudotumor Cerebri medicine.diagnostic_test business.industry Lumbar puncture Stiffness Brain Reproducibility of Results Magnetic resonance imaging medicine.disease equipment and supplies Magnetic Resonance Imaging Magnetic resonance elastography Female medicine.symptom business Nuclear medicine 030217 neurology & neurosurgery |
| Zdroj: | Clinical imaging. 51 |
| ISSN: | 1873-4499 |
| Popis: | This study determines the reproducibility of magnetic resonance elastography (MRE) derived brain stiffness in normal volunteers and compares it against pseudotumor patients before and after lumbar puncture (LP). MRE was performed on 10 normal volunteers for reproducibility and 14 pseudotumor patients before and after LP. During LP, opening and closing cerebrospinal fluid (CSF) pressures were recorded before and after removal of CSF and correlated to brain stiffness. Stiffness reproducibility was observed (r > 0.78; p < 0.008). Whole brain opening LP stiffness was significantly (p = 0.04) higher than normals, but no significant difference (p = 0.11) in closing LP measurements. No significant correlation was observed between opening and closing pressure and brain stiffness. |
| Databáze: | OpenAIRE |
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