Synthesis of some 1-Acetyl-3,5-diaryl-2-pyrazoline Derivatives and their Antimicrobial Activities

Autor: CIHAT SAFAK, AYLA TAYHAN, SELMA SARAC, NURAN YULUG
Jazyk: angličtina
Rok vydání: 1990
Předmět:
DOI: 10.5281/zenodo.6220078
Popis: Department of Pharmacutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey Department of Microbiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey Manuscript received 18 April 1989, revised 9 January 1990, accepted 30 March 1990 Title compounds, 1-acetyl-3 5-diaryl-2-pyrazolines (3a-m), were synthesised by the reaction of hydrazine hydrate withthe corresponding 1-(4-chlorophenyl)-3-aryl-2-propenones (1a- m) in acetic acid. The antibacterial and antifungal activities of the compounds were tested against some gram-positive and gram-negative bacteria and fnngi.
Databáze: OpenAIRE