Performance of the Tachyon Time-of-Flight PET Camera
| Autor: | Jian Zhou, Ronald H. Huesman, D. Wilson, William W. Moses, Chinh Vu, Jinyi Qi, Qiyu Peng, Woon-Seng Choong, Martin Janecek, J.S. Huber |
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| Rok vydání: | 2015 |
| Předmět: |
Nuclear and High Energy Physics
timing resolution Biomedical Engineering Bioengineering Scintillator time-of-flight Atomic Article Imaging phantom Particle and Plasma Physics Optics Nuclear Sensitivity (control systems) Electrical and Electronic Engineering Image resolution Physics business.industry Resolution (electron density) Molecular Order (ring theory) Coupling (probability) Nuclear & Particles Physics Other Physical Sciences Nuclear Energy and Engineering Biomedical Imaging Signal-to-noise ratio business Energy (signal processing) |
| Zdroj: | IEEE transactions on nuclear science, vol 62, iss 1 |
| ISSN: | 1558-1578 0018-9499 |
| DOI: | 10.1109/tns.2014.2375176 |
| Popis: | We have constructed and characterized a time-of-flight Positron Emission Tomography (TOF PET) camera called the Tachyon. The Tachyon is a single-ring Lutetium Oxyorthosilicate (LSO) based camera designed to obtain significantly better timing resolution than the $\sim 550~\hbox{ps}$ found in present commercial TOF cameras, in order to quantify the benefit of improved TOF resolution for clinically relevant tasks. The Tachyon’s detector module is optimized for timing by coupling the $6.15 \times 25~\hbox{mm}^2$ side of $6.15 \times 6.15 \times 25~\hbox{mm}^3$ LSO scintillator crystals onto a 1-inch diameter Hamamatsu R-9800 PMT with a super-bialkali photocathode. We characterized the camera according to the NEMA NU 2-2012 standard, measuring the energy resolution, timing resolution, spatial resolution, noise equivalent count rates and sensitivity. The Tachyon achieved a coincidence timing resolution of $314~\hbox{ps} +/- 20~\hbox{ps}$ FWHM over all crystal-crystal combinations. Experiments were performed with the NEMA body phantom to assess the imaging performance improvement over non-TOF PET. The results show that at a matched contrast, incorporating 314 ps TOF reduces the standard deviation of the contrast by a factor of about 2.3. |
| Databáze: | OpenAIRE |
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