The effect of steroids on theophylline absorption
| Autor: | G. Tatsis, D. Douratsos, D. Orphanidou, C. Mellissinos, D. Pantelakis, E. Pipini, J. Jordanoglou |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Adult
Male Chronic bronchitis medicine.medical_specialty Hydrocortisone medicine.drug_class Pharmacology Biochemistry Pharmacokinetics Theophylline Oral administration Internal medicine Bronchodilator medicine Humans Lung Diseases Obstructive Aged business.industry Biochemistry (medical) Cell Biology General Medicine Middle Aged Asthma Endocrinology Delayed-Action Preparations Choline theophyllinate Corticosteroid Female business medicine.drug |
| Zdroj: | The Journal of international medical research. 19(4) |
| ISSN: | 0300-0605 |
| Popis: | The effect of hydrocortisone on plasma theophylline concentrations was evaluated in 20 patients suffering from chronic bronchitis or stable bronchial asthma. Choline theophyllinate (400 mg) was orally administered every 12 h for 8 days and blood samples were taken every 2 h during the day for the measurement of theophylline concentrations. Intravenous bolus injections of 500 or 1000 mg hydrocortisone on day 5 or day 7, respectively, did not significantly alter plasma theophylline concentrations. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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