Triamcinolone for the Treatment of Graves Ophthalmopathy Tested With Short Tau Inversion Recovery Magnetic Resonance
| Autor: | Eduardo Jorge Prémoli, Tomás Ortiz-Basso, Ricardo García-Mónaco, Rodolfo Vigo, Maria Felisa Shokida, Mariano Sidelnik, Mariana S Vazquez-Durand |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Orbital swelling Triamcinolone acetonide Adolescent Inversion recovery Triamcinolone Injections Graves' ophthalmopathy Young Adult 03 medical and health sciences 0302 clinical medicine medicine Humans In patient Prospective Studies Prospective cohort study Glucocorticoids medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging eye diseases Intensity (physics) Graves Ophthalmopathy Ophthalmology Treatment Outcome 030221 ophthalmology & optometry population characteristics Female Surgery Nuclear medicine business Orbit Follow-Up Studies medicine.drug |
| Zdroj: | Ophthalmic Plastic & Reconstructive Surgery. 35:22-24 |
| ISSN: | 0740-9303 |
| DOI: | 10.1097/iop.0000000000001125 |
| Popis: | PURPOSE To evaluate if parabulbar triamcinolone reduces orbital swelling in patients with Graves ophthalmopathy. METHODS This is a prospective study of a series of patients with active and moderate Graves ophthalmopathy. Short tau inversion recovery magnetic resonance was used to evaluate the intensity of the extraocular rectus muscles and orbital fat, before and after the treatment with parabulbar triamcinolone. RESULTS The signal intensity ratio of the sum of the OD rectus muscles was 3.67 before treatment (95% CI, 3.26-4.09) and 2.83 after treatment (95% CI, 2.63-3.03) (p < 0.001), and of the muscles of the left orbit, 3.94 before treatment (95% CI, 3.50-4.38) and 2.85 after treatment (95% CI, 2.56-3.14) (p < 0.001). The signal intensity ratio of the fat decreased from 2.95 (95% CI, 2.69-3.21) to 2.33 (95% CI, 2.07-2.58) (p < 0.001). After treatment, there were no local or systemic complications. CONCLUSION The use of parabulbar triamcinolone reduces orbital inflammation of patients with active and moderate Graves ophthalmopathy. |
| Databáze: | OpenAIRE |
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