Reduction of catheter-related bloodstream infections in preterm infants by the use of catheters with the AgION antimicrobial system
| Autor: | Serena Elia, Carlo Dani, Giovanna Bertini, Federica Ceciarini |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Catheterization
Central Venous medicine.medical_specialty Neonatal intensive care unit medicine.medical_treatment Peripherally inserted central catheter Drug Delivery Systems Anti-Infective Agents Sepsis Humans Medicine Mechanical ventilation business.industry Infant Newborn Obstetrics and Gynecology Retinopathy of prematurity medicine.disease Surgery Catheter Intraventricular hemorrhage Bronchopulmonary dysplasia Catheter-Related Infections Anesthesia Pediatrics Perinatology and Child Health business Infant Premature Central venous catheter |
| Zdroj: | Early Human Development. 89:21-25 |
| ISSN: | 0378-3782 |
| DOI: | 10.1016/j.earlhumdev.2012.07.003 |
| Popis: | The present study aims to assess if use of a silver zeolite-impregnated umbilical catheter (AgION technology) can decrease the occurrence of catheter-related bloodstream infection (CRBSIs) in preterm infants.Infants with gestational age30weeks were randomized to receive an AgION impregnated or non-impregnated polyurethane umbilical venous catheter (UVC). The primary endpoint was the incidence of CRBSIs during the time the UVC was in place.We studied 86 infants, 41 of whom received the AgION catheter and 45 the non-impregnated catheter. During umbilical venous catheterization 2% of infants in the AgION group developed CRBSI in comparison with 22% of infants in the control group (p=0.005). AgION catheters were well tolerated and none of the patients showed signs attributable to silver toxicity.The AgION-impregnated UVCs were effective in decreasing the development of CRBSIs in preterm infants compared to non-impregnated polyurethane UVCs. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect