Effects of Traditional Chinese Medicine herbs for tonifying Qi and kidney, and replenishing spleen on intermittent asthma in children aged 2 to 5 years old
| Autor: | Wang Wenge, Zhang Junhong, Lin Meijiao, Geng Yingying, Bi Shuying, Li Hongxia |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Strengthening spleen
0301 basic medicine Male medicine.medical_specialty Reinforcing Qi and kidney Qi Placebo-controlled study Traditional Chinese medicine Placebo Kidney law.invention 03 medical and health sciences 0302 clinical medicine Airway resistance Randomized controlled trial law Internal medicine Medicine Humans Asthma Medicine(all) Medicine Chinese traditional Eosinophil cationic protein Traditional medicine business.industry General Medicine medicine.disease 030104 developmental biology medicine.anatomical_structure Treatment Outcome 030228 respiratory system Child Preschool Female business Spleen Drugs Chinese Herbal |
| Zdroj: | Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 36(1) |
| ISSN: | 0255-2922 |
| Popis: | ObjectiveTo evaluate the efficacy and safety of Traditional Chinese Medicine (TCM) herbs for tonifying Qi and kidney, and replenishing spleen on intermittent asthma in children aged 2 and 5 years.MethodsA randomized, single-blind, placebo controlled trial was conducted. Children with intermittent asthma were enrolled and their baseline conditions were measured using a questionnaire. A total of 60 participants, aged 2 to 5, were randomized into either the treatment group (n = 40) or the placebo group (n = 20). The treatment group was treated with granules of TCM herbs for tonifying Qi and kidney, and replenishing spleen, and the placebo group was given placebo granules for 3 months. The number of asthma attacks was counted and TCM syndrome scores were measured at 1, 2, 3, 6, 9, and 12 months. The airway resistance and levels of eosinophil cationic protein for the two groups were observed before and after 3 months. The results were statistically analyzed.ResultsCompared with the placebo group, the number of asthma attacks significantly decreased in the treatment group (P < 0.05). For the treatment group, the TCM syndrome scores decreased after 1 and 2 months; there was also a significant difference in scores between the two groups (P < 0.05). The difference remained after the medicine was stopped for 9 months (P < 0.05). After the 3-month treatment, compared with the placebo group, the airway resistance decreased in the treatment group (P < 0.05). No adverse events were reported in the treatment group.ConclusionThe TCM herbs for tonifying Qi and kidney, and replenishing spleen reduced the number of intermittent asthma attacks, decreased the TCM syndrome scores, and reduced the airway resistance in the children aged 2 to 5. |
| Databáze: | OpenAIRE |
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