Original Article The prevalence and diagnostic criteria of health-care associated infections in neonatal intensive care units in Turkey: A multicenter point- prevalence study

Autor: Canan Aygün, Esin Koç, M. Yekta Öncel, Mehmet Satar, Belma Saygili Karagol, Salih Çağrı Çakır, Kadir Şerafettin Tekgündüz, Nejat Narli, Sezin Unal, Yalçın Çelik, Saime Sündüz Uygun, Adil Umut Zübarioğlu, Nükhet Aladağ Çiftdemir, Demet Terek, Ayşe Ecevit, Ibrahim Murat Hirfanoglu, Emel Okulu, Didem Aliefendioğlu, Ozge Saglam, Sule Yigit, Hasan Tezer, Ayşegül Zenciroğlu, Ali Bulbul, Serdar Beken, Münevver Türkmen, Esra Onal, Nuran Üstün, Nihal Oygür, Asuman Coban, Ferit Kulali, Tugba Gursoy, Sevim Ünal, Tuğba Bedir Demirdağ, Adviye Çakıl Sağlık, Suna Oguz, Fatma Narter
Přispěvatelé: Ege Üniversitesi, Gürsoy, Tuğba (ORCID 0000-0002-6084-4067 & YÖK ID 214691), Demirdağ, Tuğba Bedir, Koç¸ Esin, Tezer, Hasan, Oğuz, Suna, Satar, Mehmet, Sağlam, Özge, Uygun, Saime Sündüz, Önal, Esra, Hırfanoğlu, İbrahim Murat, Tekgündüz, Kadir, Oygür, Nihal, Bülbül, Ali, Zübarioğlu, Umut, Üstün, Nuran, Ünal, Sezin, Aygün, Canan, Karagöl, Belma Saygılı, Zenciroğlu, Ayşegül, Öncel, M. Yekta, Sağlık, Adviye Çakıl, Okulu, Emel, Terek, Demet, Narlı, Nejat, Aliefendioğlu, Didem, Ünal, Sevim, Türkmen, Münevver Kaynak, Narter, Fatma Kaya, Çiftdemir, Nükhet Aladağ, Beken, Serdar, Çakır, Salih Çağrı, Yiğit, Şule, Çoban, Asuman, Ecevit, Ayşe, Çelik, Yalçın, Kulalı, Ferit, School of Medicine, Acibadem University Dspace
Jazyk: angličtina
Rok vydání: 2021
Předmět:
medicine.medical_specialty
animal structures
Turkey
media_common.quotation_subject
Population
Prevalence
030501 epidemiology
03 medical and health sciences
0302 clinical medicine
Hygiene
Intensive Care Units
Neonatal
Sepsis
Surveys and Questionnaires
030225 pediatrics
Intensive care
medicine
Humans
Infection control
Blood culture
education
point prevalence
media_common
Cross Infection
education.field_of_study
medicine.diagnostic_test
business.industry
Infant
Newborn
lcsh:RJ1-570
Pneumonia
Ventilator-Associated
virus diseases
lcsh:Pediatrics
health-care associated infection
medicine.disease
Medicine
Neonatology
Pediatrics
Pneumonia
Catheter
Health-care associated infection
Neonate
Point prevalence
Surveillance
Catheter-Related Infections
Pediatrics
Perinatology and Child Health
Emergency medicine
surveillance
neonate
0305 other medical science
business
Zdroj: Pediatrics and Neonatology, Vol 62, Iss 2, Pp 208-217 (2021)
Pediatrics and Neonatology
Popis: Background: healthcare-acquired infections (HAIs) in the neonatal period cause substantial morbidity, mortality, and healthcare costs. Our purpose was to determine the prevalence of HAIs, antimicrobial susceptibility of causative agents, and the adaptivity of the Centres for Disease Control and Prevention (CDC) criteria in neonatal HAI diagnosis. Methods: a HAI point prevalence survey was conducted in the neonatal intensive care units (NICUs) of 31 hospitals from different geographic regions in Turkey. Results: the Point HAI prevalence was 7.6%. Ventilator-associated pneumonia (VAP) and central line-associated bloodstream infections (CLABSI) and late onset sepsis were predominant. The point prevalence of VAP was 2.1%, and the point prevalence of CLABSI was 1.2% in our study. The most common causative agents in HAIs were Gram-negative rods (43.0%), and the most common agent was Klebsiella spp (24.6%); 81.2% of these species were extended spectrum beta-lactamase (ESBL) (+). Blood culture positivity was seen in 33.3% of samples taken from the umbilical venous catheter, whereas 0.9% of samples of peripherally inserted central catheters (PICCs) were positive. In our study, 60% of patients who had culture positivity in endotracheal aspirate or who had purulent endotracheal secretions did not have any daily FiO2 change (p = 0.67) and also 80% did not have any increase in positive end-expiratory pressure (PEEP) (p = 0.7). On the other hand, 18.1% of patients who had clinical deterioration compatible with VAP did not have endotracheal culture positivity (p = 0.005). Conclusions: neonatal HAIs are frequent adverse events in district and regional hospitals. This at-risk population should be prioritized for HAI surveillance and prevention programs through improved infection prevention practices, and hand hygiene compliance should be conducted. CDC diagnostic criteria are not sufficient for NICUs. Future studies are warranted for the diagnosis of HAIs in NICUs.
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Databáze: OpenAIRE
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