Baseline intraoperative intact parathyroid hormone levels in parathyroid surgery

Autor: Wilson I. Omesiete, David J. Terris, William S. Duke, Nathaniel J. Walsh
Rok vydání: 2017
Předmět:
Zdroj: Headneck. 41(3)
ISSN: 1097-0347
Popis: We sought to evaluate the relationship between the preoperative core-laboratory parathyroid hormone (CL-PTH) level and the baseline intraoperative PTH (IOPTH) level and assess the impact of any differences on clinical decision making in consecutive surgical patients with primary hyperparathyroidism undergoing parathyroidectomy.The CL-PTH and baseline IOPTH levels were compared. The influence of relying on either the CL-PTH or baseline PTH levels for intraoperative decision making was determined.Data were available for 316 patients. Baseline IOPTH measurements were usually higher than the CL-PTH (247 patients; 78.2%) measurements, with a mean difference of 68.2 pg/mL (P.001). Using the CL-PTH as a surrogate for the baseline parathyroid hormone (PTH) would have prolonged the operation in 23 patients (7.3%).Baseline point-of-care IOPTH levels were higher than the preoperative CL-PTH levels in75% of patients undergoing parathyroidectomy. Using the CL-PTH in lieu of an IOPTH baseline value would prolong the operation in some patients.
Databáze: OpenAIRE