Baseline intraoperative intact parathyroid hormone levels in parathyroid surgery
| Autor: | Wilson I. Omesiete, David J. Terris, William S. Duke, Nathaniel J. Walsh |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Parathyroidectomy
Male endocrine system medicine.medical_specialty Databases Factual medicine.medical_treatment Intact parathyroid hormone Clinical Decision-Making Urology Parathyroid hormone 030209 endocrinology & metabolism Mean difference 03 medical and health sciences 0302 clinical medicine Monitoring Intraoperative Medicine Humans Baseline (configuration management) Aged Retrospective Studies business.industry Middle Aged medicine.disease Hyperparathyroidism Primary Otorhinolaryngology Parathyroid Hormone 030220 oncology & carcinogenesis Female Parathyroid surgery business hormones hormone substitutes and hormone antagonists Primary hyperparathyroidism Surgical patients |
| Zdroj: | Headneck. 41(3) |
| ISSN: | 1097-0347 |
| Popis: | We sought to evaluate the relationship between the preoperative core-laboratory parathyroid hormone (CL-PTH) level and the baseline intraoperative PTH (IOPTH) level and assess the impact of any differences on clinical decision making in consecutive surgical patients with primary hyperparathyroidism undergoing parathyroidectomy.The CL-PTH and baseline IOPTH levels were compared. The influence of relying on either the CL-PTH or baseline PTH levels for intraoperative decision making was determined.Data were available for 316 patients. Baseline IOPTH measurements were usually higher than the CL-PTH (247 patients; 78.2%) measurements, with a mean difference of 68.2 pg/mL (P.001). Using the CL-PTH as a surrogate for the baseline parathyroid hormone (PTH) would have prolonged the operation in 23 patients (7.3%).Baseline point-of-care IOPTH levels were higher than the preoperative CL-PTH levels in75% of patients undergoing parathyroidectomy. Using the CL-PTH in lieu of an IOPTH baseline value would prolong the operation in some patients. |
| Databáze: | OpenAIRE |
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