Clinical Study of Different Modes of Non-invasive Ventilation Treatment in Preterm Infants With Respiratory Distress Syndrome After Extubation
| Autor: | Wenya Zhang, Qian Zhao, Hui Wu, Jingling Zhang, Yang Wang, Tao Bo, Fei Ding, Zimei Cheng |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
extubation
medicine.medical_treatment synchronized nasal intermittent positive pressure ventilation 030204 cardiovascular system & hematology Pediatrics Clinical study 03 medical and health sciences nasal continuous positive airway pressure ventilation 0302 clinical medicine 030225 pediatrics Oxygen therapy medicine Non-invasive ventilation Clinical efficacy preterm infants Original Research Mechanical ventilation Respiratory distress business.industry lcsh:RJ1-570 lcsh:Pediatrics respiratory distress syndrome Anesthesia Pediatrics Perinatology and Child Health Breathing Noninvasive ventilation business |
| Zdroj: | Frontiers in Pediatrics Frontiers in Pediatrics, Vol 8 (2020) |
| ISSN: | 2296-2360 |
| Popis: | Objective: This study aimed to investigate the clinical efficacy and safety of different non-invasive respiratory support methods in preterm infants with respiratory distress syndrome (RDS) after extubation.Methods: From Oct 2017 to 2018, 120 preterm infants were recruited from the NICUs of three hospitals. They were diagnosed with RDS and required mechanical ventilation. After extubation from mechanical ventilation, these infants were divided into NCPAP group, SNIPPV group and SNIPPV + NCPAP group. The time of non-invasive ventilation, reintubation rate within 72 h, success rate of non-invasive ventilation within 1 week, duration of oxygen therapy, hospital stay and incidence of complications were recorded and compared.Results: Compared with the NCPAP group, the SNIPPV group and the SNIPPV + NCPAP group had significantly higher rate of successful extubation and removal from non-invasive ventilation within 1 week (P < 0.05). There were no significant differences among three groups in the time of non-invasive ventilation, time of oxygen therapy, hospital stay or incidence of complications (P > 0.05).Conclusion: SNIPPV + NCPAP after mechanical ventilation is a relatively safe and effective ventilation strategy for preterm infants with severe RDS. The use of NCPAP facilitates the turnover of SNIPPV ventilators in developing countries. |
| Databáze: | OpenAIRE |
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