Psychological parameters impact health-related quality of life in mental and physical domains in adults with muscular dystrophy
| Autor: | Paul Orme, Carl J. Payton, Dawn N. O'Dowd, Christopher I. Morse, Emma L. Bostock, Dave Smith |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Adult Male media_common.quotation_subject Physical function Anxiety Muscular Dystrophies 03 medical and health sciences 0302 clinical medicine Quality of life (healthcare) medicine Humans Psychological testing Muscular dystrophy Genetics (clinical) Depression (differential diagnoses) media_common Aged business.industry Depression Self-esteem Middle Aged Physical Functional Performance medicine.disease Mental health Self Concept Muscular Dystrophy Duchenne 030104 developmental biology Neurology Muscular Dystrophies Limb-Girdle Pediatrics Perinatology and Child Health Quality of Life Female Neurology (clinical) medicine.symptom business 030217 neurology & neurosurgery Clinical psychology |
| Popis: | The impacts of potentially treatable psychological parameters on quality of life are relatively unreported in adults with Facioscapulohumeral, Becker and Limb-girdle muscular dystrophy. The purpose of this study was to compare quality of life, psychological parameters, and physical function between adults with muscular dystrophy and controls, and to examine relationships among these parameters in muscular dystrophy. Twenty-one adults with muscular dystrophy (n = 7 Becker, n = 8 Facioscapulohumeral, n = 6 Limb-girdle) and ten age-matched controls participated. Outcome measures were health-related quality of life, depressive symptoms, trait anxiety, self-esteem, physical self-worth and six-minute walk distance. Quality of life scores were lower in the muscular dystrophy groups than the control (p < .05). Depressive symptoms had the greatest association with quality of life in the Mental Health domain (r= -0.89, p < .001). Depressive symptoms also had the most associations with quality of life (7 of 10 domains), followed by trait anxiety (6 of 10 domains), physical self-worth (5 of 10 domains), self-esteem (4 of 10 domains) and six-minute walk distance (3 of 10 domains). Psychological parameters and, to a lesser extent, physical function impact quality of life in muscular dystrophy. This study provides a rationale to include psychological assessment and treatment within muscular dystrophy healthcare. |
| Databáze: | OpenAIRE |
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