Zwolle Risk Score for Safety Assessment of Same-day Discharge after Primary Percutaneous Coronary Intervention
Autor: | Bashir Ahmed Solangi, Musa Karim, Gulzar Ali, J. Shah, Mahesh Kumar Batra, Ghazanfar Ali Shah, Muhammad Hassan, Kamran A. Khan, Mehwish Zehra, Muhammad Zubair |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Framingham Risk Score business.industry medicine.medical_treatment Primary percutaneous coronary intervention Zwolle risk score Percutaneous coronary intervention ST-segment elevation myocardial infarction Early discharge Emergency medicine medicine Original Article Cardiology and Cardiovascular Medicine business Major adverse cardiac events Same day discharge |
Zdroj: | Journal of the Saudi Heart Association |
ISSN: | 1016-7315 |
Popis: | Objectives The Zwolle risk score (ZRS) has been considered to be a useful tool for the systematic evaluation of patients for early discharge after primary percutaneous coronary intervention (PCI). Therefore, aim of this study was to evaluate the clinical utility of ZRS for the same-day discharge strategy after primary PCI at a tertiary care cardiac center of Karachi, Pakistan. Methods This study was conducted at a tertiary care cardiac center between August 2019 and July 2020. Patients discharged within 24 h (same-day) of the primary PCI procedure were included. Patients were stratified as high- and low-risk based on ZRS score; low-risk (≤3) and high-risk (≥4). All patients were followed during 30-days post-procedure period for major adverse cardiac events (MACE). Results Out of 487 patients, 83.2% (405) were male and mean age was 54.6 ± 10.87 years. Mean ZRS was 2.34 ± 1.64 with 16.0% (78) patients in high-risk (≥4) group. 30-days MACE rate was observed to be 5.3% (26) with significantly higher rate among high-risk patients as compared to low-risk patients 12.8% (10) vs. 3.9% (16); p = 0.004 respectively with OR of 3.61 [1.57–8.29]. The area under the curve (AUC) of ZRS for prediction of 30-day MACE was 0.67 [95% CI: 0.58–0.77], ZRS ≥4 had sensitivity of 38.5% and specificity of 85.2% with AUC of 0.62 [95% CI: 0.50–0.74] for prediction of 30-day MACE. Conclusion ZRS showed moderate discriminating potential in identifying patients with high-risk of MACE at 30-day after same-day discharge after primary PCI. |
Databáze: | OpenAIRE |
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