Prevalence, Characteristics, Risk Factors, and Outcomes of Invasively Ventilated COVID-19 Patients with Acute Kidney Injury and Renal Replacement Therapy

Autor: Elena Moizo, Stefano Turi, Corrado Campochiaro, Alberto Zangrillo, Cristina Mattioli, Pasquale Nardelli, Paolo Silvani, Martina Crivellari, Giovanni Landoni, Marianna Sartorelli, Maria Grazia Calabrò, Fabio Ciceri, Francesco Giuseppe Nisi, Maria Luisa Azzolini, Giovanni Borghi, Marina Pieri, Antonio Dell'Acqua, Fabrizio Monaco, Martina Baiardo Redaelli, Caterina Conte, Alessandro Belletti, Ary Serpa Neto, Gabriele Valsecchi, Piera Angelillo, Evgeny Fominskiy, Cristina Barberio, Milena Mucci, Luigi Beretta, Rinaldo Bellomo, Anna Mara Scandroglio, Alfredo Ravizza, Stefano Tentori, Lorenzo Dagna, Giacomo Monti
Přispěvatelé: Intensive Care Medicine, Fominskiy, E. V., Scandroglio, A. M., Monti, G., Calabro, M. G., Landoni, G., Dell'Acqua, A., Beretta, L., Moizo, E., Ravizza, A., Monaco, F., Campochiaro, C., Pieri, M., Azzolini, M. L., Borghi, G., Crivellari, M., Conte, C., Mattioli, C., Silvani, P., Mucci, M., Turi, S., Tentori, S., Baiardo Redaelli, M., Sartorelli, M., Angelillo, P., Belletti, A., Nardelli, P., Nisi, F. G., Valsecchi, G., Barberio, C., Ciceri, F., Serpa Neto, A., Dagna, L., Bellomo, R., Zangrillo, A.
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
medicine.medical_specialty
Continuous Renal Replacement Therapy
Coronavirus disease 2019 (COVID-19)
medicine.medical_treatment
030232 urology & nephrology
Hospital mortality
030204 cardiovascular system & hematology
urologic and male genital diseases
Cohort Studies
03 medical and health sciences
0302 clinical medicine
Risk Factors
Prevalence
medicine
Humans
Hospital Mortality
Renal replacement therapy
Stage (cooking)
Aged
Ventilators
Mechanical

Coronavirus disease 2019
SARS-CoV-2
business.industry
urogenital system
Acute kidney injury
COVID-19
Hematology
General Medicine
Middle Aged
Tertiary care hospital
medicine.disease
Respiration
Artificial

Methods observational
female genital diseases and pregnancy complications
Coronavirus
Critical care
Treatment Outcome
Nephrology
Emergency medicine
Female
business
Research Article
Healthcare system
Zdroj: Blood purification, 50(1), 102-109. S. Karger AG
Blood Purification
ISSN: 0253-5068
Popis: Background: There is no information on acute kidney injury (AKI) and continuous renal replacement therapy (CRRT) among invasively ventilated coronavirus disease 2019 (COVID-19) patients in Western healthcare systems. Objective: To study the prevalence, characteristics, risk factors and outcome of AKI and CRRT among invasively ventilated COVID-19 patients. Methods: Observational study in a tertiary care hospital in Milan, Italy. Results: Among 99 patients, 72 (75.0%) developed AKI and 17 (17.7%) received CRRT. Most of the patients developed stage 1 AKI (33 [45.8%]), while 15 (20.8%) developed stage 2 AKI and 24 (33.4%) a stage 3 AKI. Patients who developed AKI or needed CRRT at latest follow-up were older, and among CRRT treated patients a greater proportion had preexisting CKD. Hospital mortality was 38.9% for AKI and 52.9% for CRRT patients. Conclusions: Among invasively ventilated COVID-19 patients, AKI is very common and CRRT use is common. Both carry a high risk of in-hospital mortality.
Databáze: OpenAIRE