Bis(imidazolium) salts derived from amino acids as receptors and transport agents for chloride anions
| Autor: | Belén Altava, Laura González-Mendoza, Roberto Quesada, Jorge Escorihuela, Elsa Hernando, Cristian Vicent, Santiago V. Luis, M. Isabel Burguete |
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| Rok vydání: | 2015 |
| Předmět: |
General Chemical Engineering
Chemistry Organic Salt (chemistry) Medicinal chemistry Chloride Compostos orgànics Síntesi chemistry.chemical_compound medicine Life Science Organic chemistry POPC VLAG chemistry.chemical_classification Liposome amino acids Organic Chemistry chloride anions Química orgánica General Chemistry Organische Chemie Transmembrane protein Amino acid chemistry Proton NMR bis(imidazolium) Titration Aminoàcids medicine.drug |
| Zdroj: | Repositorio Institucional de la Universidad de Burgos (RIUBU) instname Repositori Universitat Jaume I Universitat Jaume I González-Mendoza, Laura Altava, Belén Burguete, M. Isabel Escorihuela Fuentes, Jorge Hernando, Elsa Luis, Santiago V. Quesada, Roberto Vicent, Cristian 2015 Bis(imidazolium) salts derived from amino acids as receptors and transport agents for chloride anions Rsc Advances 2015 5 34415 34423 RODERIC. Repositorio Institucional de la Universitat de Valéncia RSC Advances : An international journal to further the chemical sciences, 5(43), 34415-34423 RSC Advances : An international journal to further the chemical sciences 5 (2015) 43 |
| ISSN: | 2011-2890 2046-2069 |
| Popis: | The binding properties of bis(imidazolium) hosts 1a–c derived from amino acids towards different anions have been studied by 1H NMR titration experiments in 95 : 05 CD3CN : H2O at 303 K, ESI-MS and theoretical calculations. Among this family, the salt 1c showed a strong and high selectivity for chloride anions. Transmembrane chloride transport activity has also been studied for the three bis(imidazolium) based transporters in POPC liposome models, and compound 1a was identified as an active chloride/nitrate exchanger. Ministerio de Econom´ıa y Competitividad (CTQ2011-28903-C02-01), Generalitat Valenciana (PROMETEO 2012/020) and Universitat Jaume I (P11B2013-38), Consejer´ıa de Educaci´on de la Junta de Castilla y Le´on (Project BU340U13) and Fundaci´o la Marat´on de TV3 |
| Databáze: | OpenAIRE |
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