THE INHIBITION OF PLASMIN, PLASMA KALLIKREIN, PLASMA PERMEABILITY FACTOR, AND THE C'1r SUBCOMPONENT OF THE FIRST COMPONENT OF COMPLEMENT BY SERUM C'1 ESTERASE INHIBITOR
| Autor: | Oscar D. Ratnoff, George B. Naff, Jack Pensky, D. Ogston |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1969 |
| Předmět: |
Chemical Phenomena
Plasmin Hereditary angioneurotic edema Immunology Vascular permeability Esterase Article Capillary Permeability Alpha-Globulins medicine Immunology and Allergy Humans Fibrinolysin Alpha globulin Blood coagulation test Chemistry Esterases Kallikrein Complement System Proteins Biochemistry Kallikreins Blood Coagulation Tests Esterase inhibitor medicine.drug circulatory and respiratory physiology |
| Zdroj: | The Journal of Experimental Medicine |
| ISSN: | 1540-9538 0022-1007 |
| Popis: | The fraction of human serum designated as C'1 esterase inhibitor is known to inhibit the action of C'1 esterase, a plasma kallikrein, and PF/Dil, an enzyme in plasma enhancing cutaneous vascular permeability. In the present study, C'1 esterase inhibitor has been found to block the actions of plasmin and the C'1r subcomponent of the first component of complement, and to retard the generation of PF/Dil. No inhibition of blood clotting or of the generation of plasmin was demonstrable. |
| Databáze: | OpenAIRE |
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