Chromium in Drinking Water: Association with Biomarkers of Exposure and Effect
| Autor: | Eleni Sazakli, Athanasia Mouzaki, Cristina M. Villanueva, Kyriakos Maltezis, Manolis Kogevinas, Michalis Leotsinidis |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Adult
Chromium Male medicine.medical_specialty epidemiological study Cross-sectional study Health Toxicology and Mutagenesis lcsh:Medicine Physiology chemistry.chemical_element Physical examination Motor Activity Article Water Supply health effects Epidemiology Medicine Humans biomarkers of exposure and effect Water intake Triglycerides Aged chromium oral consumption medicine.diagnostic_test Greece business.industry Drinking Water lcsh:R Sodium Public Health Environmental and Occupational Health chromium blood Middle Aged Diet Cross-Sectional Studies High triglycerides chemistry chromium hair Population study Female business Biomarkers Water Pollutants Chemical Low sodium Hair |
| Zdroj: | International Journal of Environmental Research and Public Health Volume 11 Issue 10 Pages 10125-10145 International Journal of Environmental Research and Public Health, Vol 11, Iss 10, Pp 10125-10145 (2014) |
| ISSN: | 1660-4601 |
| DOI: | 10.3390/ijerph111010125 |
| Popis: | An epidemiological cross-sectional study was conducted in Greece to investigate health outcomes associated with long-term exposure to chromium via drinking water. The study population consisted of 304 participants. Socio-demographics, lifestyle, drinking water intake, dietary habits, occupational and medical history data were recorded through a personal interview. Physical examination and a motor test were carried out on the individuals. Total chromium concentrations were measured in blood and hair of the study subjects. Hematological, biochemical and inflammatory parameters were determined in blood. Chromium in drinking water ranged from < 0.5 to 90 μg·L−1 in all samples but one (220 μg·L−1), with a median concentration of 21.2 μg·L−1. Chromium levels in blood (median 0.32 μg·L−1, range < 0.18–0.92 μg·L−1) and hair (median 0.22 μg·g−1, range 0.03–1.26 μg·g−1) were found within “normal range” according to the literature. Personal lifetime chromium exposure dose via drinking water, calculated from the results of the water analyses and the questionnaire data, showed associations with blood and hair chromium levels and certain hematological and biochemical parameters. Groups of subjects whose hematological or biochemical parameters were outside the normal range were not correlated with chromium exposure dose, except for groups of subjects with high triglycerides or low sodium. Motor impairment score was not associated with exposure to chromium. |
| Databáze: | OpenAIRE |
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