Etiology and outcome of second trimester non-immunologic fetal hydrops
| Autor: | S, Heinonen, M, Ryynänen, P, Kirkinen |
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| Rok vydání: | 2000 |
| Předmět: | |
| Zdroj: | Acta Obstetricia et Gynecologica Scandinavica. 79:15-18 |
| ISSN: | 1600-0412 0001-6349 |
| DOI: | 10.1080/j.1600-0412.2000.079001015.x |
| Popis: | This investigation was undertaken to study the conditions resulting in midtrimester fetal hydrops and to evaluate its overall prognosis as regards counseling purposes.The etiology of midtrimester non-immune fetal hydrops was retrospectively evaluated as regards cases detected in singleton pregnancies (n=58) from January 1987 through December 1996. The condition was diagnosed by way of routine biochemical and ultrasonographic screening of a pregnant population.The rate of diagnosed midtrimester fetal hydrops was 1 in 1700 pregnancies and the overall survival rate in this usually unexpected condition was less than 10%. Various chromosomal and fetal structural abnormalities dominated as a cause of fetal hydrops, representing 44.8% and 43.1% of the cases, respectively. Infection caused only 6.9%. The underlying etiology remained unknown in only three cases. However, in 78% the diagnosis was already known prenatally.Although the overall prognosis is poor, knowledge of the primary etiology is important to determine a rational therapeutic strategy. If the results of routine investigations rule out malformation and abnormal chromosomes, follow-up serial ultrasonographic assessment may indicate that the hydropic state is transient, carrying a somewhat better prognosis. |
| Databáze: | OpenAIRE |
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