Crohn’s disease complicated by relapsed extranodal Hodgkin’s lymphoma: prolonged complete remission after unmanipulated PBPC autotransplant
| Autor: | R Scalone, Alessandra Crescimanno, Ferdinando Porretto, Maurizio Musso, V Polizzi, F. Bondi |
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| Rok vydání: | 2000 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Disease Hematopoietic stem cell transplantation Gastroenterology Crohn Disease hemic and lymphatic diseases Internal medicine medicine Humans Transplantation Homologous Transplantation Crohn's disease business.industry Hematopoietic Stem Cell Transplantation Hematology medicine.disease Hodgkin's lymphoma Hodgkin Disease Ulcerative colitis digestive system diseases Lymphoma surgical procedures operative Immunology Complication business |
| Zdroj: | Bone Marrow Transplantation. 26:921-923 |
| ISSN: | 1476-5365 0268-3369 |
| Popis: | Crohn's disease and ulcerative colitis are inflammatory bowel diseases (IBD), which are thought to result from an inappropriate immunologic (autoimmune) response to luminal antibodies. Allogeneic stem cell transplantation (SCT) performed for coincidental diseases is able to cure both leukaemia and Crohn's disease. Autologous SCT is currently performed worldwide for severe autoimmune diseases (SADs) because of its reduced transplant-related mortality (TRM). We report the case of a 30-year-old male patient with a 10-year history of severe Crohn's disease, who developed Hodgkin's disease and received an unmanipulated peripheral blood autologous transplant. Three years after the transplant the patient is in complete treatment-free remission of both diseases. |
| Databáze: | OpenAIRE |
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