Is Helicobacter pylori a cause of atrial fibrillation?
| Autor: | A. S. Montenero, Peter Andrew |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
biology business.industry Peptic C-reactive protein Atrial fibrillation Inflammation Helicobacter pylori medicine.disease biology.organism_classification Systemic inflammation Gastroenterology Pathogenesis Chronic infection Internal medicine cardiovascular system biology.protein medicine Cardiology Molecular Medicine medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Future Cardiology. 2:429-439 |
| ISSN: | 1744-8298 1479-6678 |
| DOI: | 10.2217/14796678.2.4.429 |
| Popis: | Inflammation has been implicated in the pathogenesis of cardiovascular diseases. C-reactive protein, a sensitive marker of systemic inflammation, has recently been reported to be significantly higher in patients with atrial fibrillation (AF) compared with a control group with no history of atrial arrhythmia. Elevated C-reactive protein levels in patients with AF reflects an underlying inflammatory process. Histological anomalies in the atria of patients with AF have also been observed. These anomalies may have an inflammatory basis, although it is not known if any structural changes within the atria are a cause or a consequence of the arrhythmia. Ongoing chronic infection(s) has been suggested as a possible cause of the inflammatory process demonstrated in patients with AF. Helicobacter pylori, a Gram-negative bacterium more commonly known for infecting the gastric mucosa and causing peptic ulcers, is a noncardiac factor that has been controversially reported to be associated with cardiovascular diseases. This article gives a brief overview of AF and specifically explores the recent evidence that suggests that Helicobacter pylori infection causes AF. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|