Clinical outcome of catheter salvage in neutropenic cancer patients with catheter-related infection
| Autor: | Jae-Hoon Song, Kyong Ran Peck, Young Eun Ha, Eun-Jeong Joo, Seung-Ji Kang, Cheol-In Kang, Doo Ryeon Chung, So Yeon Park, Won-Ki Kang, Mi-Kyong Joung |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Microbiology (medical) endocrine system medicine.medical_specialty Neutropenia Fever of Unknown Origin Immunocompromised Host Patient age Neoplasms medicine Humans Aged Retrospective Studies Leukopenia Bacteria General Immunology and Microbiology business.industry Cancer Bacterial Infections General Medicine Emergency department Middle Aged medicine.disease Catheter-Related Infections Surgery Lymphoma Catheter Treatment Outcome Infectious Diseases Female medicine.symptom business |
| Zdroj: | Scandinavian Journal of Infectious Diseases. 43:258-263 |
| ISSN: | 1651-1980 0036-5548 |
| DOI: | 10.3109/00365548.2010.544669 |
| Popis: | Catheter-related infections (CRI) cause significant morbidity and mortality in cancer patients, particularly during episodes of chemotherapy-induced neutropenia. This study was performed to evaluate clinical features and outcomes of CRI in neutropenic cancer patients.We retrospectively analyzed clinical characteristics and outcome of febrile neutropenic cancer patients with CRI who visited the emergency department from January 1996 to June 2007.A total of 51 neutropenic cancer patients with CRI were identified and 53 organisms were isolated from culture specimens. The mean ± standard deviation patient age was 50 ± 15 y and the most common underlying disease was lymphoma (n = 27, 53%). Gram-positive organisms accounted for 77% of all isolated pathogens (41/53). Initial catheter salvage was attempted in 38 episodes of CRI, of which 20 were successful. In the current study the overall success rate of catheter salvage attempts was 52.6%. The failure rate of catheter salvage was significantly higher in CRI caused by Gram-negative pathogens than by Gram-positive pathogens.Although catheter salvage should be cautiously attempted for cancer patients with CRI, it might not be a treatment option for neutropenic cancer patients with CRI caused by Gram-negative bacteria. |
| Databáze: | OpenAIRE |
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